SNHLSensorineural Hearing Loss
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Early diagnosis and timely management of SNHL is important as early intervention will have a large impact on the treatment outcomes.
Current screening programs implemented in some hospitals, called "targeted screening," in which babies who fail newborn screening programs are tested for CMV, are not sufficient to achieve the goal of identifying babies who will need follow-up for early detection of SNHL or vision abnormalities, or possibly early antiviral therapy (Valcyte; valganciclovir), because only a small portion of those who eventually develop SNHL are currently identified by the targeted screening programs.
However, to the best of our knowledge, the association between serum endocan levels and presence or severity of SNHL has not been investigated.
A second objective was to determine the prevalence and degree of severity of meningitis-related SNHL at Red Cross War Memorial Children's Hospital (RCWMCH), a paediatric tertiary hospital in Cape Town, SA.
SNHL is defined as hearing loss due to damage or dysfunction of the inner ear (as opposed to other structures of the ear).
A total of 69 children (aged 6 to 24 months) diagnosed with profound SNHL were included.
The aim of the present study is to conduct a medical audit of subjective outcomes of bilateral simultaneous CI in children with severe bilateral congenital SNHL which would serve as a reference scale for future studies.
The disease can manifest in profound SNHL, hypothesized to result from disruption of synchronous activity of the cochlear nerve.
Sensorineural hearing loss (SNHL) is one of the most common long-term disabilities worldwide in preterm infants, with an incidence of 0.7-17.5% for very preterm newborns (<32 weeks) [1-3].
The diagnoses of BD can be delayed by years when audiovestibular impairment is the presenting symptom in the absence of classical signs and symptoms, as in the case of a 66-year-old man with peripheral bilateral vestibulopathy and severe sudden SNHL as disease onset, reported by White and colleagues [52].
The majority of hearing disorders occur due to the death of either inner ear hair cells (HCs) or spiral ganglion neurons (SGNs), thus leading to sensorial neural hearing loss (SNHL).
It is characterised by early-onset or congenital sensorineural hearing loss (SNHL) followed by development of RP.7 Bardet-Biedl syndrome (BBS), the second most common form includes RP, polydactyly, obesity, renal abnormalities and mental retardation.8