George's Respiratory Questionnaire total score; TLC = total lung capacity; UCSD SOBQ = University of California, San Diego Shortness of Breath Questionnaire; VA = Department of Veterans Affairs.
2] 43 [+ or -] 6 CT Emphysema Score 16 [+ or -] 4 LVEF, [greater than or equal to] 45% 1,566 (97) MOS SF-36 PCS Score (range 8-56) 28 [+ or -] 7 MOS SF-36 MCS Score (range 12-76) 52 [+ or -] 10 SGRQ-TS (range 17-96) 57 [+ or -] 13 6MWT Distance (m) (range 35-750) 335 [+ or -] 98 Maximal CPET Workload (W) 33 [+ or -] 20 UCSD SOBQ Total Score (range 8-120) 66 [+ or -] 19 6MWT Borg 5 [+ or -] 2 CPET Borg 6 [+ or -] 2 6MWT = 6-minute walk test; BD = bronchodilator; Beck = Beck Depression Inventory; BMI = body mass index; Borg = Borg score for breathlessness; CPET = cardiopulmonary exercise testing; CT = computed tomography; DLCO = single-breath diffusing capacity of the lung for carbon monoxide; [FEV.
The current UCSD SOBQ is the result of several modifications of a questionnaire described in 1987 by Archibald and Guidotti (5) which assessed shortness of breath during activities of daily living (ADL) in individuals with chronic obstructive pulmonary disease.
The reliability and validity of the UCSD SOBQ was assessed in 54 individuals (32 male, 22 female) participating in pulmonary rehabilitation.
Validity was determined in the same group of subjects by comparing UCSD SOBQ scores to other measures.
This author was not able to find specific mention of the minimal detectable change in the UCSD SOBQ in the literature.
The responsiveness to change was determined by comparing changes in the UCSD SOBQ scores after pulmonary rehabilitation to changes in the Chronic Respiratory Questionnaire-Dyspnea (CRQ-Dyspnea) score and the Transitional Dyspnea Index (TDI).
The MCID has been determined by expert consensus and by calculating effect size, SEM, and comparing agreement between UCSD SOBQ and CRQ-Dyspnea and TDI.
To assess dyspnea during activities of daily living, the UCSD SOBQ can be used during an initial evaluation as a baseline measurement and during re-evaluations to detect change.