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Related to SOD1: SOD2, SOD3, G93A
SOD1superoxide dismutase 1 (gene)
References in periodicals archive ?
SOD1 und amyotrophic lateral sclerosis: mutation and oligomerization.
Only few studies have been conducted to study the polymorphisms present in SOD1 gene in association with RA.
Interestingly, 100 nM quercetin or rutin induced a significant increase of all the tested genes encoding antioxidant enzyme expression, and in the case of rutin, all concentrations tested augmented in a significant manner SOD1, CAT and GR expression (p<0.
In addition the alignment of the complete SOD1 gene sequence between the Murrah and the Mediterranean breeds revealed nine potential SNPs which could be candidates for validation in commercial buffalo populations.
In the Cell Stem Cell study, Eggan and postdoctoral fellow Evangelos Kiskinis led an effort to make stem cell lines from two women with ALS who have SOD1 mutations to compare human biology and mouse biology.
Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation," Molecular Biology of the Cell, vol.
Professor Pamela Shaw, Director of SITraN, and her research team worked in collaboration with a fellow world leading MND scientist Dr Caterina Bendotti and her group at the Mario Negri Institute for Pharmacological Research in Milan, Italy investigated two mouse models of MND caused by an alteration in the SOD1 gene, a known cause of MND in humans.
60) Mutant SOD1 protein specifically causes motor neuron death, but the mechanism remains controversial.
SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments.
However, the SOD1 mutation only accounts for 1%-2% of ALS cases overall (20% of familial cases and 10% of sporadic cases; Wijesekera & Leigh, 2009).