SPIEMSolid-Phase Immune Electron Microscopy
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The samples were then reexamined by SPIEM (see Table 3).
Comparison of direct EM with UC and SPIEM enrichment on 40 urine samples showed the benefit of enrichment procedures (see Fig.
Our comparison of direct EM with UC or SPIEM enrichment clearly showed increased sensitivity after enrichment.
4) Nonstandard abbreviations: EM, electron microscopy; UC, ultracentrifugation; BMT, bone marrow transplantation; SPIEM, solid-phase immunoelectron microscopy; BKV, human polyomavirus BK; and JCV, human polyomavirus JC.