SPRCASolid Phase Red Cell Adherence
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A study of D negative combat trauma patients massively transfused with D positive RBCs (7) confirmed that gel column agglutination is superior to other commonly used serology methods, including SPRCA, in the detection and monitoring of mixed-field reaction patterns.
In 2005, the SPRCA method primarily (65.4%) used a 2-cell screen, but that decreased to 24.6% in 2010, whereas the use of a 3-cell screen increased to 61.1% by 2010 (see Table 4).
Use of SPRCA and LMWT remained constant at 1% or less each.