To examine which parameters could be clinically useful for assessing the risk of poststroke HF, we evaluated the predictive properties of all variables independently associated with poststroke HF as well as of SPTH
(a significant independent determinant when subjects with history of stroke are compared with patients without CVD) and living in a permanent RCF (although not an independent but a significant and practically important indicator of poststroke HF).
We obtained the following information from medical records for all study patients: sex, age, occupation, history of close contact with a TB patient (defined as a household member or colleague with TB), health insurance, TB treatment history, symptom duration before first evaluation at SPTH, presence of cavities on chest radiographs, current alcohol use, current smoking, sputum smear test results, and HIV status.
Sputum samples from all hospitalized TB patients in SPTH were collected before the start of TB therapy and then cultured on Lowenstein-Jensen culture medium.
We included the following variables in bivariate analysis: sex, age, occupation, history of close contact with a TB patient, health insurance, TB treatment history, symptom duration before first evaluation in SPTH, presence of cavity on chest radiograph, current alcohol use, current smoking, diagnostic sputum smear test results, HIV status, and Beijing genotype.
This research project was approved by the Chinese Ethical Committee for TB Operational Research, Chinese Center for Disease Control and Prevention, and SPTH. Patients were asked for written informed consent before drug susceptibility testing and genotyping were performed.