SSADASense, Search And Destroy Armor
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This result does not mean that breath holding has no influence on ocular blood flow, but it clearly shows that with the SSADA software, slowing the movement of red blood cells does not influence the measured vessel density as long as the red blood cells keep moving in the capillaries of the peripapillary RNFL.
SSADA was employed to improve the signal-to-noise ratio by splitting the spectrum to generate multiple repeat OCT frames from the two original repeat OCT frames [13].
Third, the SSADA technique does not directly measure the perfusion of optic disc; however, measures the peri-ONH region, which reflects perfusion of the ONH.
In the OCTA system (RTVueXR Avanti; Optovue, Inc., Fremont, CA, USA), AngioVue applied SSADA to detect vessels with blood flow through the intrinsic motion contrast provided by the flowing erythrocytes, making it possible to noninvasively obtain three-dimensional mapping of the retina and choroidal microvasculature [18, 19].
The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm in OCT scanning and the en face OCT technique, which helps visualize frontal cross-sections of the retina at various layers, contributed to the development of the noninvasive optical coherence tomography angiography for visualizing blood flow in retinal and choroidal vessels [22, 23].
The split-spectrum amplitude decorrelation angiography (SSADA) algorithm [29] revealed the blood flow areas by the decorrelation of two cross-sectional 3D raster scans in order to improve the signal-to-noise ratio and minimize motion artifacts.
Using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm, blood flow and the microvascular network can be visualized by decorrelating the motion of red blood cells from the static tissues without the need for contrast injection.