In contrast, SSLR is not associated with circulating immune complexes or hypocomplementemia.
The lesions quickly evolve to the classic purpuric lesions of SSLR over the following 24-48 hours.
Several medications are associated with SSLR, but cefaclor is most frequently implicated in 0.2% of treated children.
The diagnosis of SSLR is primarily clinical, formulated based on the constellation of characteristic lesions, fever, adenopathy, facial edema, and/or arthralgia in conjunction with recent history (within 7-21 days) of offending medications or agents.
An extensive variety of cutaneous conditions bearing a resemblance to SSLR were considered in the differential, including urticaria multiforme, Kawasaki disease, erythema multiforme, and urticarial vasculitis.
Urticarial vasculitis (UV), morphologically similar to SSLR and UM, causes persistent urticarial-like plaques that last longer than 24-48 hours and resolve with bruising.
Erythema multiforme (EM), a hypersensitivity reaction usually triggered by infections (most commonly herpes simplex virus), also may appear morphologically similar to SSLR. These lesions also persist for longer than 24-48 hours and often have a target appearance with central duskiness that sometimes can blister.
Other disorders commonly presenting with similar extracutaneous manifestations to SSLR and concomitant dermatitis were further excluded based on the morphological appearance of the lesions and other clinical dissimilarities.
Safety, Security and the Well-Being of Sex Workers: A Report Submitted to the House of Commons Subcommittee on Solicitation Laws (SSLR).
"Sex Work Policy: An Integrated Approach." Invited presentation to the House of Commons Subcommittee on Solicitation Laws (SSLR), February 7, Ottawa Canada.
(9) There are two noteworthy exceptions to this point: the first is wish's nationally unique Aboriginal health and safety project for women working in the sex trade, a project that is delivered in partnership with Vancouver Native Health as well as Vancouver Coastal Health (discussed by wish Executive Director Kate Gibson before the 29 March 2005 public meeting of the SSLR
, the joint federal Subcommittee on Solicitation Laws of the Standing Committee on Justice, Human Rights, Public Safety and Emergency Preparedness [15, 30]).