Furthermore, based on information obtained from analyses of changes in CDR-SB and amyloid PET SUVr
values from ADNI data, in a sub-population analysis of patients with baseline SUVr
range between 1.4 and 1.9 who were identified in this study as being expected to have a higher rate of disease progression, there was 72% less decline in CDR-SB for patients in the 50 mg total group arm (n=10) versus placebo (n=5).
(2) To obtain a more accurate indication of age-related brain regions, different thresholds of voxel values were set and compared correlations between SUVR mean and age using Pearson correlation.
Next, data from the 255 healthy subjects were utilized to calculate SUVR mean  of the targeted brain regions generated with different [sigma], by using the paracentral lobule (AAL 69 and AAL 70) as the reference regions .
Az, Es, and Sr are the area under the receiver operating characteristics curve, effect size, and SUVR ratios, respectively.
The simulated TACs and the predicted SUVR were compared to the clinical data of 9 clinically applied tau radiotracers.
Demographic, clinical, and individual regional SUVR
data are presented in Table 1.
The [sup.18]F-FDG SUVR
images were acquired by normalizing the uptake value of the whole brain to the uptake value of the cerebellum from the [sup.18]F-FDG PET data.
At the end of treatment, the four patients in the placebo group had an average increase of 21% in their standard uptake value ratio (SUVR
), measured by PET, compared with baseline.
[Toxoplasmosis among certain groups of the population of the Varna region.] Suvr
Med (Sofia) 1962;13:18-23.
(Standard Uptake Value Ratio) calculates the ratio of strength of accumulation of PET tracer in a region of interest in the brain to an area of the brain (reference region) which shows low and stable accumulation of PET tracer.
Furthermore, the amyloid status of all participants is shown in Table 1; the cerebellar gray matter was used as the reference region and the standard uptake value ratio (SUVR
) cutoff value was set to 1.15 [20, 21].
The composite SUVR
for the anterior and posterior right and left cingulate, plus right and left frontal, lateral temporal, and parietal regions, combined and normalized to the whole cerebellum, did no change significantly in the solanezumab group or the placebo group in either study.