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References in periodicals archive ?
In other tissues and disease processes, for example damage to neurons in demyelinating diseases such as multiple sclerosis (MS), the same semaphorin has an opposite effect on outgrowth of cells, preventing the regeneration and remyelination of damaged neurons.
This may mean that while semaphorin 3F is attracting immature myelin- making cells to sites needing repair, increased signals from semaphoring 3A are preventing repair from occurring.
Growth cone collapse induced by semaphorin 3A requires 12/15-lipoxygenase.
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis.
This common variant lies on chromosome 5 near a gene known as semaphorin 5A, which is thought to help guide the growth of neurons and their long projections called axons.
His group finds that some axons have docking sites for both connectin and semaphorin II, two such guidance molecules.
They have also identified a possible method of regulating the growth of new nerves and axons through a protein called semaphorin 4F.