Peromyscus maniculatus is the main reservoir of Sin Nombre virus
, which is the leading cause of HPS in the United States (Monroe et al., 1999).
(16) The investigators concluded the dramatic increase in high-desert rainfall associated with the 1992-1993 El Nino weather pattern contributed to the risks of Sin nombre virus
exposure in the region and that annual precipitation predictions would be of value in designing disease prevention campaigns.
Remote sensing and Geographic Information Systems: charting Sin Nombre virus
infections in deer mice.
A rapid immunoblot strip assay (RIBA) has been developed to detect antibodies to Sin Nombre virus
Two of the 101 specimens had antibody reaction with Sin Nombre virus
(SNV) and related hantaviruses.
white-looted mice) for Sin Nombre virus
and its variants and Sigmodon
Antibodies against Puumala virus and Sin Nombre virus
cross-react, whereas SEOV as member of the other serogroup cross-reacts with Hantaan virus, Dobrava-Belgrade virus, and Saaremaa virus.
Prevalence of antibodies to Sin Nombre virus
in humans living in rural areas of southern New Mexico and western Texas.
Following the identification of Sin Nombre virus
(SNV) as the etiologic agent of HPS in the United States in 1993, many other hantaviruses have been identified in the Americas (3-6).
For this outbreak, a confirmed case was defined as detection of 1) a febrile illness and hantavirus (Sin Nombre virus
) specific antibodies in serum, or 2) virus antigen in postmortem tissue using immunohistochemistry, in a person who had stayed overnight in Yosemite National Park during June 1-August 28, 2012.
In North America, Sin Nombre virus
(SNV) is the most widespread hantavirus and is of primary public health importance because of the high case-fatality rate (>35%) associated with hantavirus pulmonary syndrome (HPS) (1).