Inoue et al., "Circulating levels of soluble Fas ligand
and soluble Fas in patients with chronic obstructive pulmonary disease," Respiratory Medicine, vol.
Arici, "Elevated soluble Fas ligand
levels may suggest a role for apoptosis in women with endometriosis," Fertility and Sterility, vol.
Godfrey et al., "Therapeutic use of soluble fas ligand
ameliorates acute and recurrent herpetic stromal keratitis in mice," Investigative Ophthalmology and Visual Science, vol.
Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand
. Am J Physiol Lung Cell Mol Physiol 2001; 280:L298-305.
Plasma soluble Fas antigen and soluble Fas ligand
in controls and HIV-1 infected individuals Subjects Soluble Fas (ng/ml) Range n Mean SD Min Max Controls 15 2.77 0.375 2.193 3.4467 HIV-1 ([dagger])CDC A 13 3.08 0.998 1.8044 4.9572 CDC B 12 3.26 0.672 2.316 4.392 ([dagger]) CDC C 12 3.28 0.753 2.24 4.999 Subjects *Soluble Fas ligand (ng/ml) Range n Mean SD Min Max Controls 15 0.073 0.046 0.026 0.112 HIV-1 ([dagger])CDC A 13 0.138 0.065 0.100 0.300 CDC B 12 0.125 0.045 0.089 0.204 ([dagger]) CDC C 12 0.117 0.058 0.04 0.201 * Controls vs HIV; P<0.001.
The aim of this study was to determine the changes in complete blood count (CBC), NK cell count and activity, perforin expression, and Fas and soluble Fas ligand
(sFas-L) levels in immunocompetent children with VZV infection and define any possible relations between the levels and development of varicella complications.
Chemotactic activity of soluble FAS ligand
Serum levels of soluble Fas ligand
, which can trigger apoptosis in such Fas-expressing tissues as the kidney, liver, and heart, also appear to be increased in HLH (51).
Membrane Fas ligand kills human peripheral blood T lymphocytes and soluble Fas ligand
blocks the killing.