McElrath and colleagues have found that proteins contained in circulating microparticles in the blood may hold important clues about spontaneous preterm birth
. Circulating microparticles (CMPs) are tiny packages secreted by cells that can contain proteins, RNAs and other molecules that act as messages that can be transmitted from one cell to another.
"The Preterm Prediction Study: Maternal Stress Is Associated With Spontaneous Preterm Birth
at Less Than Thirty-Five Weeks' Gestation.
Infection is known to be an important cause of spontaneous preterm birth
Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: association with increased risk of spontaneous preterm birth
. Obstet Gynecol.
"Premature cervical ripening plays a significant role in spontaneous preterm birth
," said Dr.
Dolin et al., "Uterocervical angle: a novel ultrasound screening tool to predict spontaneous preterm birth
," American Journal of Obstetrics & Gynecology, vol.
Periodontal disease and spontaneous preterm birth
: A case control study.
Transvaginal ultrasound (TVU) cervical length (CL) screening for prediction and prevention of spontaneous preterm birth
(SPTB) is among the most transformative clinical changes in obstetrics in the last decades.
Urinary phthalate metabolites were positively associated with preterm birth, and associations were stronger for spontaneous preterm birth
In previous studies, RSA has been reported to have a similar pathogenesis to that of placental dysfunction complications, such as preeclampsia, intrauterine fetal death, oligohydramnios, small for gestational age children, placental abruption, and spontaneous preterm birth
. It also correlates with placental ischemia caused by placenta implantation insufficiency during the first trimester [12-14], immune imbalance of Thl/Th2 and Thl7/Treg on maternal-fetal interface, insufficient invasion of extravillous trophoblastic cells, and uterine spiral artery dysfunction.
Prenatal depression, prenatal anxiety, and spontaneous preterm birth
: a prospective cohort study among women with early and regular care.
Cerclage is recommended for women with prior spontaneous preterm birth
who are already receiving progesterone supplementation and CL is <25 mm.