Conventional Echocardiographic Findings SSc (n=47) HC (n=20) p LVEDD (cm) 4.95[+ or -]0.22 4.91[+ or -]0.17 0.45 LVESD (cm) 3.09[+ or -]0.2 3.05[+ or -]0.2 0.51 EF (%) 60.1[+ or -]2.18 60.7[+ or -]1.83 0.30 RAD (cm) 3.75[+ or -]0.27 3.49[+ or -]0.34 0.001 RVD (cm) 2.34[+ or -]0.18 2.19[+ or -]0.15 0.002 TAPSE (cm) 2.02[+ or -]0.33 2.96[+ or -]0.51 0.0001 SPAP (mmHg) 30.78[+ or -]4.83 23.35[+ or -]3.23 0.001 TRV (m/sn) 2.62[+ or -]0.31 2.02[+ or -]0.19 0.001 LVEDD: left ventricular end-diastolic diameter; LVESD: left ventricular end-systolic diameter; EF: ejection fraction; RAD: right atrial diameter; RVD: right ventricular diameter; TAPSE: tricuspidal annular plane systolic excursion; SPAP: systolic pulmonary artery pressure
There was fall in the mean systolic pulmonary artery pressure
at the six months follow echocardiogram.
of patients with SPAP>35 mmHg (number) 19 EF: Ejection fraction; [FEV.sub.1]: forced expiratory volume in 1st second; FVC: forced vital capacity; LVEDD: left ventricular end diastolic dimension; LVESD: left ventricular end systolic dimension; PEFR: peak expiratory flow rate; RV Sm: right ventricular systolic myocardial velocity sPAP: systolic pulmonary artery pressure
Systolic pulmonary artery pressure
measured with echocardiography and sPAP measured with an ultrasound phase-probe were correlated (r=0.83; p=0.001).
During treatment, the systolic function of the left and right ventricles (according to the end-diastolic left-ventricular size (KDRLZH), right ventricle (KDRPZH), left ventricular ejection fraction (LVEF), right ventricular ejection phase (FIPZH), index thicker anterior wall of the right ventricle (ITPPZH), systolic pulmonary artery pressure
(MPAP), as well as diastolic function (E/LVA; E/BPH) in patients from the first group returned to normal, and in patients from the control group was carrying a tendency to normalization.
Additionally, catheterization profile data between diastolic and nondiastolic dysfunctions did not reveal any statistically significant variables between the two groups, including systolic pulmonary artery pressures
(sPAP) (P = 0.77), diastolic pulmonary artery pressures (dPAP) (P = 0.68), mean pulmonary artery pressures (mPAP) (P = 0.84), mean PCWP (P = 0.17), cardiac output (P = 0.23), cardiac index (P = 0.21), and left ventricular ejection fraction (P = 0.99)(Table 3).
She and her associates prospectively analyzed data from 121 patients referred to the Medical University of Vienna between April 2007 and October 2008 for clinical and transthoracic echocardiographic suspicion of precapillary PH (systolic pulmonary artery pressure
of 36 mm Hg or greater).
Two dimensional echocardiography revealed a dilated right atrium and right ventricle, abnormal septal motion suggestive of right ventricular overload, normal left ventricular systolic function, moderately severe tricuspid regurgitation and moderately severe pulmonary hypertension (estimated peak systolic pulmonary artery pressure
of 70 mm Hg).
To test this hypothesis, the investigators used echocardiography to measure systolic pulmonary artery pressure
in 11 children aged 6-8 years who were born to preeclamptic mothers from La Paz, Bolivia, where the elevation is 12,000-13,000 feet above sea level.
In addition, studies [sup], showed that plasma brain natriuretic peptide (BNP) correlated with systolic pulmonary artery pressure
(sPAP) in IPF patients and could be used as a biomarker to assess the prognosis of IPF patients with PH.
Also, systolic pulmonary artery pressure
(PAP) was evaluated echocardiographically by measuring tricuspid valve pressure gradient adding to the left atrial pressure.
In the second part of the study, 3 men and 11 women with sickle cell disease and pulmonary hypertension took 100 mg sildenafil three times a day for at least 3 months to see if the drug had any impact on systolic pulmonary artery pressure
and functional capacity.