T-LGL

Acronym	Definition
T-LGL	T Cell Large Granular Lymphocyte

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References in periodicals archive ?

In spite of the fact that the majority of T-LGL leukemia cases are of [alpha][beta] type, there are rare cases of [gamma][delta] T-LGL leukemia [2, 13].

[gamma][delta] T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature [gamma][delta] T-Cell Malignancies

Although neutropenia and recurrent bacterial infections are frequent and are considered to be a main cause of morbidity and mortality in patients with T-LGL leukemia, this was not the case with our patient.

It is believed that sustained immune stimulation and a dysregulation of apoptosis underlies T-LGL leukemia pathogenesis, which is why immunosuppressive therapy remains the mainstay of treatment [4].

Few studies reported the use of purine analogs, polyche-motherapy, antithymocyte globulin and other regimens in refractory or relapsed T-LGL leukemia [1,2].

The case of T-cell large granular lyphocyte leukemia presented as transfusion dependent anemia with sustained response to cyclosporine a therapy: case report/T-celijska leukemija velikih granulisanih limfocita sa klinickom slikom transfuziono zavisne anemije i protrahovanim terapijskim odgovorom na ciklosporin a: prikaz slucaja

Like HSTL, T-LGL can occur in the setting of immunosuppression and manifests with neutropenia, anemia, and/or thrombocytopenia.

Hepatosplenic T-Cell Lymphoma: A Clinicopathologic Review With an Emphasis on Diagnostic Differentiation From Other T-Cell/Natural Killer-Cell Neoplasms