TCBVTotal Cerebral Blood Volume
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The research showed the association between VAT and TCBV was most robust and was also independent of BMI and insulin resistance.
Moreover, a subset of 198 individuals underwent volumetric brain MRI to evaluate 2 recognized markers of early AD pathology, the temporal horn volume (THV), which is an inverse measure of hippocampal volume, and the total cerebral brain volume (TCBV).
[2] Nonstandard abbreviations: AD, Alzheimer disease; CNS, central nervous system; NMDA, N-methyl-D-aspartic acid; LTP, long-term potentiation; THV, temporal horn volume; TCBV, total cerebral brain volume; TNF, tumor necrosis factor; ApoE, apolipoprotein E; APP, amyloid precursor protein.