TCCSGTri-County Celiac Support Group (Michigan)
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All patients received intravenous MTX continuously at 3 g/[m.sup.2]/12 hrs or 24 hrs, or 5 g/[m.sup.2]/24 hrs with folic acid rescue following the protocol of the Tokyo Children's Cancer Study Group (TCCSG) L99-15 [28], ALL-BFM 95 [29], or NHL B9604 [30].
All assessable weekly 3 g/[m.sup.2] HD-MTX courses following the treatment protocol of TCCSG L99-15 for standard or high risk ALL patients totaled 149.