For data on relative weights and lengths of organs, TiBS and TeBS
; GS and VAng; and LLD, a completely randomized experimental design in a 3 x 2 (diets and ages) factorial arrangement model, considering each killed broiler as the observational unit, was used and analyzed with GLM, FREQ and GLIMMIX, and MIXED procedures, respectively.
Numerous undifferentiated terminal ends, presumed to be TEBs
, were noted upon examining whole mounts at 3 months, which is unusual for this age of CD-1 mice (S.
Tissue-engineered bone (TEB
) represents a promising approach to overcome these problems and is becoming an increasingly popular choice for repairing bone defects.
The S548 million TEBS
transaction, designed to support more than 8,800 affordable-housing units, represents the second-largest TEBS
transaction in Freddie Mac history, according to Mike May, multifamily senior vice president at Freddie Mac.
After staining with Carmine Alum (0.2% carmine, 0.5% aluminum potassium sulfate), the samples were coated with polyacrylate, placed in a water-filled petri dish, and viewed under a stereomicroscope (Stemi DRC, Carl Zeiss AG) to count the number of terminal end buds (TEBs
Although laboratories vary in their methods for reporting altered MG development, the primary approach has been morphological assessment of the entire fourth or fifth abdominal MG fat pad mounted flat on a slide, fixed, stained, defatted, and permanently affixed to the slide as a "whole mount." Whole mounts allow an assessment of total and relative abundance of mammary terminal ductal structures (i.e., TEBs
, terminal ducts, alveolar buds, and lobules), extension of the epithelial cells through the fat pad, and branching patterns and density at different times during development (e.g., Fenton et al.
By PND42, both groups with chronic drinking-water exposures (control + 5 ppb PFOA, 1 mg/kg + 5 ppb PFOA) displayed significantly reduced gland development relative to controls (Table 4) that was characterized by an excess of terminal end buds (TEBs
) (Figure 3).
2002), which extends the period in which the rapidly proliferating progenitor cells of the terminal end buds (TEBs
) are susceptible to carcinogenic insult (Birnbaum and Fenton 2003).
Typically, at PND33, glands 4 and 5 have grown together, and differentiation of terminal end buds (TEBs
) is apparent in control animals.
The parameters examined include number and area of terminal end buds (TEBs
), area subtended by the ductal tree, and ductal extension measured as the distance from the midpoint of the lymph node to the leading edge of the ductal tree.
Proliferation of primitive ductal structures in the newborn breast leads to branching and terminal end buds (TEBs
(68) suggested that TCDD treatment in utero potentiates the carcinogenic effects of DMBA by increasing the number of terminal end buds (TEBs
) at the time of the DMBA injection at 50 days of age; the TEBs
are suggested to be the target sites for the carcinogenic effects of chemical initiators (102).