TEM8Tumor Endothelial Marker 8
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By targeting TEM8, we can potentially create a therapy against cancer," said Stephen Fernando, who recently completed his doctoral studies.
This is the first time that any team of researchers have targeted cancer cells through protein binding to TEM8.
Part of the "fusion protein" created by the UF group binds to TEM8, and the other which promotes thrombosis, or blood clotting.
"We felt that TEM8 was an ideal target because it was inside the vessel, preferentially expressed there and unique," Fletcher said.