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The major effect of the procoagulant inhibitors, anti-thrombin (AT), activated protein C (APC), and tissue factor pathway inhibitor (TFPI) on inflammation is to:
- tissue factor pathway inhibitor (TFPI), an endogenous anticoagulant molecule, specifically inhibits the growth of endothelial cells, which makes it an appropriate candi-date for development as an antiangiogenic drug
34), the "commune system was detrimental to [sic] and the HRS has been conducive to an increase in TFPI, and there was an outward shift of the production frontier following the dismantlement of the commune system".
Ex vivo studies in which concentration of the same molecules was measured directly in the sera obtained from both groups of varicose patient showed that the samples from EVLA patients contained lower concentration of ICAM-1, E-selectin, and P-selectin and higher concentration of uPA, PAI-1, and TFPI, as compared with the serum from CVS patients.
 Nonstandard abbreviations: TF, tissue factor; FVIIa, activated factor VII; TM, thrombomodulin; PC, protein C; EPCR, endothelial protein C receptor; APC, activated PC; PS, protein S; AT, antithrombin; TFPI, tissue factor pathway inhibitor; tPA, tissue plasminogen activator; uPA, urokinase plasminogen activator; PAI, plasminogen activator inhibitor; PI, plasmin inhibitor; TAFI, thrombin activatable fibrinolysis inhibitor; ROTEM/TEG, thromboelastometry/thromboelastography; T2MR, T2 magnetic resonance.
Though we have observed decreased TFPI-1 levels in NSCLC patients, our results seem to disprove the reported results of elevated TFPI in solid tumor diseases .
 Nonstandard abbreviations: HT, hormone therapy; WHI, Women's Health Initiative; HERS, Heart and Estrogen/progestin Replacement Study; CVD, cardiovascular disease; CEE, conjugated equine estrogens; MPA, medroxyprogesterone acetate; MI, myocardial infarction; VTE, venous thromboembolism; RR, relative risk; WISDOM, Women's International Study of long Duration Oestrogen after Menopause; OR, odds ratio; Lp(a), lipoprotein(a); IL-6, interleukin-6; MMP-9, matrix metalloproteinase-9; CRP, C-reactive protein; TFPI, tissue factor pathway inhibitor.
The reaction consisted of 30 mM Tris-HCl (pH 8.4), 75 mM KCl, 2 mM Mg[Cl.sub.2], 200 [micro]M each deoxyribonucleoside triphosphate, and 1.25 U of Platinum Taq, with factor II primers each at 0.5 [micro]M, factor V and TFPI primers each at 0.3 [micro]M, and all others present at 0.2 [micro]M.
[4.] Nonstandard abbreviations: TF, tissue factor; AMI, acute myocardial infarction; PTCA, percutaneous coronary transluminal angioplasty; MI, myocardial infarction; [F.sub.1.2], prothrombin fragment 1.2; FPA, fibrinopeptide A; TAT, thrombin-antithrombin; PAI, plasminogen activator inhibitor; vWF, von Willebrand factor; t-PA; tissue plasminogen activator; TM, thrombomodulin; S-TM, soluble thrombomodulin; PAF, platelet activator factor; TNF, tumor necrosis factor; and TFPI, tissue factor pathway inhibitor.
Antihuman muscle-specific creatine kinase (CKm) monoclonal antibody (mouse Ig[G.sub.1], MAB5564), antihuman tissue factor pathway inhibitor (TFPI) monoclonal antibody (mouse Ig[G.sub.2B], MAB29741), antihuman mucosal addressin cell adhesion molecule 1 (MADCAM1) monoclonal antibody (mouse Ig[G.sub.1], MAB6056), and antihuman soluble interleukin 1 receptor like protein (ST2/ IL1R4) polyclonal antibody (goat IgG, AF523) were purchased from R&D Systems.
On the top of gene list ranked by ascending adjusted p value there are EGR1, FOSB, PTPRT, SELE, FOS, ENPP2, TFPI, ZFP36, and others.
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