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In contrast, Liu et al (24) found that thyroid stiffness was weakly related to TSH and TGAb and was not correlated with T3, T4 or TPOAb.
TgAb were determined by chemiluminescence microparticle immunoassay (ARCHITECT i2000SR).
TSH, TPOAb and TgAb levels were significantly decreased in patients treated with the combined myo-inositol/selenium after six months.
The positive rates of TPOAb and TgAb of pregnant women in the observation group were higher than in the control group (P<0.05).
There was a positive correlation between thyroid volume and serum fT4, fT3, TRAb, TPOAb, and TgAb levels (p=0.001, r=0.426; p=0.001, r=0.50; p=0.04, r=0.26; p=0.001, r=0.42; p=0.001 r=0.42; respectively; Table 3).
Currently, most of the studies concerning the thyroid tissue and CVR focused on thyroid hormones (i.e., TSH, [FT.sub.3], and [FT.sub.4]) instead of the direct role of thyroid autoimmunity (i.e., TPOAb positivity and TgAb positivity).
test result normal range WBC 9.8 3.6~9.6 x 10^3/[micro]L Hb 16.1 13.2~17.2 g/dL PLT 271 148~339 x 10^3/[micro]L CK 120 62~287 U/L AST 17 13~33 U/L ALT 22 6~30 U/L ALP 207 115~359 U/L Glucose 105 70~109 mg/dL T-chol 190 128~219 mg/dL LDL 122 <120 mg/dL ACE 10.1 8.3~21.4 U/L TSH 0.934 0.340~4.220 [micro]IU/mL FT4 1.38 0.77~1.59 ng/dL FT3 2.75 2.24~3.94 pg/mL thyroglobulin 6.57 [less than or equal to] 33.7 ng/mL TRAb (CREIA) 1.47 <2.0 IU/L TPOAb (CREIA) 2.2 <9.4 IU/mL TgAb (CREIA) 10.0 [less than or equal to] 54.6 IU/mL TSAb 146 [less than or equal to] 120%
TgAb and TPOAb were determined by electrochemiluminescence immunoassay (ECLIA) using Roche ECLusys Anti-Tg and Anti-TPO (Roche Diagnostics GmbH, Mannheim, Germany).
Abbreviations AMI: Acute myocardial infarction T3: Triiodothyronine FT3: Free triiodothyronine T4: Thyroxine FT4: Free thyroxine TSH: Thyroid-stimulating hormone TGAB: Thyroglobulin TMAB: Thyroid microsomal antibody EF: Cardiac ejection fraction NT-proBNP: N-terminal probrain natriuretic peptide MACE: Major adverse cardiovascular events GRACE: The Global Registry of Acute Coronary Events HR: Heart rate CKMB: MB isoenzyme of creatine kinase HbA1c: Hemoglobin A1c BP: Blood pressure AST: Aspartate transaminase CHF: Chronic heart failure PCI: Percutaneous coronary intervention CABG: Coronary artery bypass graft CCB: Calcium channel blocker.
TgAb assessment should be concomitantly performed with Tg (1-3) and, if detected, a TG method resistant to TgAb should be used (3).
The performance indicators to study the effects of such interventions used the following ratios of the requests for related tests: AST to alanine transaminase (AST/ALT); AGA to antitissue transglutaminase antibodies (AGA/anti-tTG), TgAb to antithyroid peroxidase antibodies (TgAb/TPOAb),TBIL/ALT, GGT/ALT, iron to ferritin, FT4 to thyroid-stimulating hormone (FT4/TSH), ESR to C-reactive protein (ESR/CRP), and urea to creatinine.
Antibodies against TPO (TPOAb) and Tg (TgAb) are able to cause destruction of thyroid cells due to antibody dependent cell cytotoxicity.
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- Tg cells
- TG INN
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- TGA VSD
- Tgag Broad
- Tgamma cells