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While TGCA data did not provide any clues, the tissue sample database revealed some variations in gene expression; the researchers found that patients with a high BMI showed reduced expression of a gene called fatty acid synthase (FASN), compared with those with a normal BMI.
Myostatin haplotype distribution in different breeds (cross) Non-meat Breeds Double Haplotype Sequence Huyang (71) Kazak (48) Beltex (7) Haplo1 CGAG 23.24 6.25 Haplo2 CGAA 42.88 Haplo3 CGCG 11.27 17.71 Haplo4 CGCA 42.88 Haplo5 CAAG Haplo6 CACG Haplo7 TGAG 23.24 43.75 14.24 Haplo8 TGAA Haplo9 TGCG 42.25 32.29 Haplo10 TGCA / / / Haplo11 TAAG Haplo12 TACG Muscle Meat Breeds Haplotype Bx H (32) Dorper (56) MPMF (127) MF (23) Haplo1 21.88 58.04 39.76 43.48 Haplo2 39.06 Haplo3 17.86 29.53 19.57 Haplo4 10.94 Haplo5 2.76 Haplo6 4.72 Haplo7 21.87 10.71 14.57 10.87 Haplo8 6.25 Haplo9 13.39 4.72 26.09 Haplo10 / / / / Haplo11 0.39 Haplo12 3.54 "/" means haplo10 was not present in the studied sheep populations, and animal numbers are in brackets after the breed.
(1989) demonstrated that if pure-line components are evaluated in the same experiment as the blends, then GBA can be partitioned into two components, GYA and TGCA. The GYA represents the innate yielding ability of a cultivar grown as a pure line, and the TGCA is the additional mean competitive response of a cultivar calculated as the difference between the GBA and the GYA.
Choosing the most efficient strategy for evaluating and selecting genotypes for use in blends requires knowledge of the relative importance of GYA, TGCA, and SCA effects in blends.
In this model, [Y.sub.hij] is a mean value for a blend of genotypes i and j over replications at one environment, [micro] is the general mean effect, [[rho].sub.h] is the hth environmental effect, [[tau].sub.i] is the deviation of the ith pure-line genotype from the mean of all pure lines (two times GYA), [[delta].sub.i]/2 is the TGCA of the ith genotype (in blends), [[gamma].sub.ij] is the SCA of genotypes i and j when grown together, and [[epsilon].sub.hij] is a genotype-by-environment interaction effect.
Comparison of the relative importance of variation in GYA, GBA, TGCA, and SCA effects can guide breeding efforts aimed at developing improved cultivar blends.
Variation among TGCA effects was also not significant in both experiments (Tables 4-7).
See also Tully, Aug 26 1853; TGCA, RG 1/4, box 1 folders 106.
Object of DNA code (they are all in 5'-3' direction from code left to right) Initiator [I.subv.1] = GCAG sequence Spacer [X.sub.0] = TCGG, [X.sub.1] = CGCA, [X.sub.2] = sequence TCAT, [X.sub.3] = GTGG, [X.sub.4] = TCTT, [X.sub.5] = TGCA, [X.sub.6] = TGGA, [X.sub.7] = CGTA Terminator [I.sub.2] = AACC sequence Atomic [p.sub.1] = CCGC, [q.sub.1] = ATCC, [p.sub.2] = proposition CAAA, [q.sub.2] = GGGA, [p.sub.3] = TTAC, [q.sub.3] = ATAT [m.sub.1] = [p.sub.1] [conjunction] [p.sub.3] = GTGA, [m.sub.2] = [q.sub.1] [conjunction] [p.sub.3] = GACC, [m.sub.3] = [p.sub.2] [conjunction] [q.sub.3] = AACG, [m.sub.4] = [q.sub.2] [conjunction] [q.sub.3] = GACG TABLE 19: Checking for [[psi].sub.4]: the encoding of FSA [A.sub.4] of formula, where sto() means WC.
Since 33.1% of cases harbored genetic loss of VHL components other than VHL, and TGCA mutation data indicated a VHL mutation rate of only 2%, inactivation of other VHL elongin BC complex components is likely involved in VHL elongin BC complex dysfunction in PCC and this could impact HIF1-target expression (Figures 2(b) and 2(c)).