TIIA

AcronymDefinition
TIIAThe International Investment Advisor (Egypt)
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TIIA down-regulates survivin expression at the transcriptional and proteasomal degradation levels
2A, treatment with TIIA for 24 h reduced survivin protein expression without altering the expression of Bd-2 protein family, including Bd-2 itself, Bcl-xL anti-apoptotic protein and Bax pro-apoptotic protein (Fig.
The upstream signaling initiated by TIIA to induce survivin down-regulation was further examined.
If a decrease in survivin expression is crucial for TIIA to trigger apoptosis, survivin overexpression should reverse this effect.
We then tested whether the TIIA induced sensitization to TRAIL in these cells.
As TIIA enhances the effects of TRAIL, we next probed whether survivin downregulation by TIIA accounts for this effect.
However, this is the first study showing that TIIA is a survivin inhibitor and that a decrease in survivin expression is essential for TIIA's effects on apoptosis induction and TRAIL sensitization (Fig.
In addition, TIIA can inhibit survivin expression in a dose-dependent manner at various levels, including transcription and proteasomal degradation.
H0 nao rejeitada, ou seja, pode-se afirmar que para os sujeitos avaliados nao ha diferenca estatistica entre os segundos limiares identificados tanto na Ventilometria quanto no TIIA com relacao as cargas de trabalho.
O presente estudo investigou a possibilidade de identificar as cargas de trabalho referentes aos limiares atraves do TIIA.
Mediante os resultados encontrados no presente estudo, verificou-se que o TIIA parece ter sido suficiente para a identificacao das cargas de trabalho referentes tanto ao Primeiro quanto ao Segundo Limiar.
2] 1 11,0 11,5 2 5,1 5,2 3 8,0 8,0 4 7,0 6,8 5 9,0 8,8 6 10,5 10,6 7 4,5 5,0 8 6,1 6,2 9 6,5 6,5 10 7,1 7,0 11 8,0 8,5 12 8,0 8,0 13 6,4 6,4 14 8,5 10,0 15 6,5 5,8 16 4,5 4,2 17 11,0 12,0 18 6,6 6,0 19 7,0 7,0 20 5,6 5,1 Tabela 6 Anova de fator unico LV2 versus 12 RESUMO Grupo Contagem Soma Media Variancia Coluna 1 20 146,9 7,35 3,74 Coluna 2 20 148,6 7,43 4,92 ANOVA Fonte da variacao SQ GL MQ F valor-P F critico Entre grupos 0,07 1 0,07 0,02 0,90 4,10 Dentro dos grupos 164,45 38 4,33 Total 164,52 39 Tabela 7 Correlacao entre Ventilometria versus TIIA Segundo Limiar Coluna 1 Coluna 2 Coluna 01 1 Coluna 02 0,98 1 [r.