TIP47Tail-Interacting Protein of 47
References in periodicals archive ?
NASDAQ:MAXM)(SSE:MAXM) today announced the publication of an article in the Journal of Molecular Cancer Therapeutics (4:761-771, 2005), which describes the discovery of a class of apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazoles and their molecular target, TIP47, an IGF-II receptor binding protein, as a novel pathway for activation of apoptosis.
Maxim scientists had reported on the identification of TIP47 and the structure activity relationship of these newly discovered anti-cancer agents at the annual meeting of the American Association of Cancer Research in April, 2005.
A presentation entitled "Identification of the molecular target for tumor selective apoptosis-inducing 3,5-diaryl-oxadiazole compounds" reports on the identification of TIP47, an IGF-II receptor binding protein, as the molecular target for this series of novel apoptosis inducers.