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The TMAD model yielded multiple negative [C.sub.A] NO values, the interpretation of which is unclear (results not presented).
Our classification of the time spent by the participants in each microenvironment was based on the TMAD records.
Protein isolation after GEMS or TMAD. Tissue powder (50-100 mg) was mixed with 300 [micro]L of ice-cold PBS/1% CHAPS, transferred to a 10-mL glass tube (Fisher) and combined with 300 [micro]L of PBS [137 mmol/L NaCl, 2.7 mmol/L KCl, 10 mmol/L [Na.sub.2]HP[O.sub.4] x 2[H.sub.2]O, 1.76 mmol/L K[H.sub.2]P[O.sub.4], pH 7.4]/CHAPS rinsate from the original powder container.
From the reviewed research on payload-based anomaly detection, TMAD  and McPAD  are the two commonly used approaches.
The bonds are payable from a first-priority lien on all pledged revenues of CAE, secured by a first mortgage on the financed facilities and a cash-funded debt service reserve sized to transaction maximum annual debt service (TMADS).
There is also a debt service reserve (DSR) cash-funded to transaction maximum annual debt service, defined as transactional maximum annual debt service excluding the transaction's final double principal payment (TMADS) of about $4.1 million.
On a consolidated basis, transaction maximum annual debt service (TMADS) coverage in fiscal 2017 was 1.3x after payment of the subordinate management fee.
ADEQUATE COVERAGE: Per Fitch's charter school rating criteria, the calculation of debt service coverage includes transaction maximum annual debt service (TMADS) coverage on the series 2011 bonds.
HIGH DEBT BURDEN: CAE's debt burden remains high; TMADS rose to 27.7% of fiscal 2017 operating revenue and coverage of TMADS from operations fell to less than 1x.
The series 2010 bonds are secured by pledged revenues of CCCS, backed by a mortgage on the property and facilities leased by the school and a debt service reserve (DSR) cash-funded to transaction maximum annual debt service (TMADS) of about $4.1 million.
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