The purpose of this study was to determine whether or not TNF
alpha is associated with prognosis and disease activity in patients with hepatitis by establishing a correlation between infection activity index and TNF
alpha in patients with CHC.
For patients with predominantly axial disease that is active and insufficiently responsive to NSAID treatment, a biologic DMARD should be considered, specifically a TNF
Decreased resistance of TNF
receptor p55 and p75 deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivo.
The -308 polymorphism in the tumour necrosis factor (TNF
) gene promoter region and ex vivo lipopolysaccharide-induced TNF
expression and cytotoxic activity in Chilean patients with rheumatoid arthritis.
In test tube studies, the researchers treated human monocytes and macrophages, cells that have a key role in inflammatory diseases, with TNF
and then challenged these cells with LPS.
monoclonal antibodies or soluble TNF
receptors neutralize TNF
Se ha demostrado que existen diferentes tasas de sintesis de TNF
alfa in vitro e in vivo entre los individuos, por lo que puede asociarse con la presencia de cierto polimorfismo genetico.
308 tumor necrosis factor (TNF
) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF
An inflammatory protein, TNF
is elevated after acute episodes--heart attack, stent placement, heart transplant--and during chronic heart diseases, such as congestive heart failure.
Using gold nanoparticles as a targeting drug delivery system, TNF
will be specifically delivered to tumors.
She fed cuprizone, an agent that sparks myelin loss, into mice lacking the TNF
-alpha protein or the molecules TNF
receptor 1 and 2 (TNFR1, TNFR2) that assist the protein to attack cells.