TNFR:Fc - What does TNFR:Fc stand for? The Free Dictionary
References in periodicals archive
protein is a potent inhibitor of tumor necrosis factor alpha (TNF-alpha), a key mediator of inflammation.
Data from preclinical studies conducted in an animal model of inflammatory arthritis demonstrated that a single injection of rAAV encoding a soluble form of the rat TNFR:Fc
vector into the ankles of arthritic rats resulted in a significant reduction in ankle and hind paw swelling as measured by arthritis index scores.
In these studies, the rat TNFR:Fc
gene, which was cloned by Targeted Genetics in 1998, was delivered using the Company's adeno-associated virus (AAV) vectors.