TNFR1

AcronymDefinition
TNFR1Tumor Necrosis Factor Receptor 1
TNFR1Tumor Necrosis Factor Alpha Receptor-1
References in periodicals archive ?
2010) Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1 or TNFR2.
Results also show that whereas soluble TNFR1 was independent of BCG dose, soluble TNFR2 was released in a BCG dose dependent manner.
There was no correlation among TNF-[alpha], TNFR1, and TNFR2 even when controlling for TR.
The loss of expression of TNFR1 explains TNF-[alpha] unresponsiveness, and resistance to TRAIL may be due to overexpression of the antiapoptotic protein c-FLIP and frequent loss of the proapoptotic protein BID.
O receptor TNFR1 e similar (APO-1/Fas) ao receptor CD95, que apresenta uma sequencia 80 aminoacidos, quando presente na regiao intracelular e referida como "dominio da morte", esta regiao e responsavel pela transmissao do sinal de inducao da citocina TNF-[alpha].
TNFR1 is expressed on OLGs, microglia, or astrocytes in culture [43-44] and may be important in demyelination in vivo.
TNFR1 levels on scene and at hospital admission were higher in more severely injured patients.
When cuprizone was stopped in mice lacking TNFR1, myelin started to form again, indicating this receptor was not crucial to myelin repair.
Mechanistic study revealed that the combination treatment increased the TNFR1 expression and decreased mitochondrial membrane potential in MDA-MB-435 and MDA-MB-231 cells (Yeruva et al.