TNNI1Troponin I, Slow-Twitch Skeletal Muscle Isoform
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The amounts of troponin T1 (Tnnt1), troponin I (Tnni1), and tropomyosin 2 (Tpm2) were significantly higher in the skeletal muscle of mice treated with FSDTAE relative to mock group mice (Figure 4).
Tnni1 (slow skeletal muscle troponin I) is also the component of the troponin complex and key regulatory protein of contractile function in skeletal muscle.
The results confirmed the previously published data, with FLJ10350 and TNNI1 being significantly up-regulated and PIPPIN being significantly down-regulated (see the online Data Supplement).