These virulence genes are mainly associated with host cell recognition and invasion (invA, orgA, prgH, tolC
, sopB, pefA), intracellular survival and growth in reticuloendothelial tissues (pagC, spvC), survival within macrophages (spiA, msgA), entry into non-phagocytic cells and killing of macrophages (spaN, sipB), and iron acquisition (ironN) (MOHAMED et al., 2014; SKYBERG et al., 2006).
The ratings on TOLC
's guaranteed bonds are based entirely on irrevocable and unconditional guarantees provided by its parent company, Japan-based ORIX Corporation (A-/Stable).
as an important bacterial virulence mechanism such as the invasion of human macrophages, biofilm formation, and maintenance of the membrane integrity of the bacteria in comparison with that the wild type.
Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC
. Antimicrob Agents Chemother.
Da, Sw tolk 'translator', MHG tolc
, tolke, 'interpreter') was employed in the sense man during the late ME period.
Bangkok: Fitch Ratings (Thailand) has assigned a final National Long-Term Rating of 'AAA(tha)' to Thai ORIX Leasing Company Limited's (TOLC
) THB1.30 billion guaranteed bonds.
In total 22 OMPs were identified by MALDI-TOF/MS analysis which includes TbpA, HgbA, PM0336 (HgbB), HasR, IroA, Oma87 (PM1992), HP-KCU-10206, HP AAUPMB 08244, HP AAUPMB 21592, HP AAUPMB 19766, AAUPMB 11295, HmbR, long-chain fatty acid transport protein, 47 kDa protein, PM1069 (OMP P1 precursor protein), TolB, TolC
, HexD, CexD, OmpA, PM786 (Omp34), OmpH (39 kDa protein), and glycerophosphodiester phosphodiesterase.
The AcrB efflux pump belongs to the resistance-nodulation-cell division (RND) superfamily and acts in association with two types of proteins: the outer membrane channel (TolC
) and a periplasmic 'adaptor' protein (AcrA).
These genes include aggA and aafA (encoding for adhesions); aap (for dispersin); aatA (for TolC
); aggR (for regulation of aggregation); astA, set1A, and sen (for toxins),fyuA (for iron recruitment); agn43 (for antigen 43); and genes encoding for serine protease autotransporter toxins such as pet and sat.
Ers talwm, efo pob car arall, doedd dim angen poeni am sut r'on i yn ei yrru, na sawl tolc
fyddai yn ei gael.