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Forensic parameters and allele frequencies of 15 autosomal STR loci (D8S1179, D21S11, D7S820, CSF-IPO, D3S1358, THOl, D13S17, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) are shown in table 1.
The STR profile of CSF1PO, D13S317, D16S539, D5S818, D7S820, TH01, vWA, TPOX, and amelogenin showed a 100% match between used HTR8/SVneo and the ATCC STR database profile ( specifications).
En el presente trabajo se encontraron las mayores frecuencias alelicas para cada marcador genetico analizado como se presenta a continuacion: Para el marcador D3S1358 el alelo 18 presento la mayor frecuencia (0.44), TH01 el alelo 6 (0.58), D21S11 alelo 30 (o.37), D18S51 alelo 12 (0.27), Penta E alelo 14 (0.25), D5S818 alelo 11 (0.60), D13S317 alelo 12 (0.33), D7S820 alelo 11 (0.58), D16S539 alelo 12 (0.31), CSF1PO alelo 10 (0.34), Penta D alelo 11 (0.29), VWA alelo 16 (0.62), D8S1179 alelo 14 (0.43), TPOX alelo 8 (0.55) y FGA alelo 24 (0.39).
Only 3/15 loci (D13S317, vWA and TPOX) appear to have appreciable null allele frequencies and 5 (CSF1PO, D3S1358, Penta D, Penta E and THO1) showed no evidence of null alleles at all.
The distributions of specific alleles of TH01, TPOX, CSF1PO, D3S1358, D13S317, D18S51, and FGA in cases with impulsive violent behavior were significantly different from those of the controls.
The allelic frequencies of four loci (D7S820, D13S317, TH01, TPOX) were compared with data sets from six Amazonian populations, seven Andean and two Panamanian populations previously reported (15-18).
Forensic Candidate Match Locus Unknown Offender Stringency D8S1179 13 13, 14 Moderate D21S11 28, 31.2 28, 31.2 High D7S820 12 10, 12 Moderate CSF1PO 10, 12 10 Moderate D3S1358 15, 17 15, 17 High TH01 8 7, 8 Moderate D13S317 9, 12 9 Moderate D16S539 11, 12 12 Moderate VWA 17 15, 17 Moderate TPOX 8, 11 8 Moderate D18S51 24 16, 24 Moderate D5S818 9, 12 12 Moderate FGA 24, 25 24, 25 High Using U.S.
United States population data on the multiplex short tandem repeat loci--HUMTHOI, TPOX, and CSFIPO--and the variable number tandem repeat locus D1S80.
"Our laboratory has observed flanking sequence mutations in several STR loci, including vWA reported here, D16S539, and TPOX. Other laboratories have recently reported flanking sequence mutations at D13S317 and D7S820." Id.
(8) La distribucion de las frecuencias alelicas estimadas en el presente estudio (Cuadro 2a, 2b) fue concordante con los hallazgos de estos autores para los sistemas STRs autosomicos: CFS1PO, TH01, TPOX, vWA, D13S317, D7S820, D16S539, D3S1358, D21S11, D18S51, PENTA E y PENTA D (p> 0.082) pero no con los sistemas D5S818, FGA y D8S1178 (p<0.05).
Suppose only one of the 13 CODIS (Combined DNA Index System) markers in an evidence profile displays three alleles (call it marker TPOX) and all other markers display one or two alleles (excluding identical twins, a 13-marker profile from a single-source sample is typically considered sufficient for source identification).