TRAF6


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AcronymDefinition
TRAF6Tumor Necrosis Factor Receptor-Associated Factor 6 (protein)
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References in periodicals archive ?
Bowie, "IRAK-2 participates in multiple Toll-like receptor signaling pathways to NF[kappa]B via activation of TRAF6 ubiquitination," The Journal of Biological Chemistry, vol.
Natural Products with Toll-Like Receptor 4 Antagonist Activity
CYLD deubiquitylates TRAF6, which transduces the RANK-mediated signal [99].
Deubiquitinating Enzymes and Bone Remodeling
In order to investigate the relevance of the hub genes and NS, the expression levels of PIK3CA, TGFBR2, CDKN1B, KRAS, E2F3, TRAF6, and CHUK were further analyzed.
Potential Genes and Pathways of Neonatal Sepsis Based on Functional Gene Set Enrichment Analyses
(2014) NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6. Mucosal Immunol.
Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders
First description and expression analysis of tumor necrosis factor receptor-associated factor 6 (TRAF6) from the swimming crab, Portunus trituberculatus.
Mannan oligosaccharides as prebiotics in crustacean aquaculture
MyD88 activates TNF receptor-associated factor 6 (TRAF6), which stimulates the IKB kinase (IKK) complex; consequently, phosphorylated nuclear transcription factor (NF-KB) translocates from the cytoplasm to the nucleus (Turner et al., 2012).
High Grain Diet Triggers Inflammation in the Goat Uterus: A Comprehensive Regulation Diet Modulates the Immune Response
Antonioli et al., "mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6," Nature Cell Biology, vol.
MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1
In sepsis induced cardiac injury and dysfunction, miR-146a can attenuate NF-kB dependent inflammatory signaling by targeting IRAK and TRAF6 in cardiomyocytes and monocytes [155].
MicroRNA as a Therapeutic Target in Cardiac Remodeling
pylori are associated with cell cycle progression and proliferation (p14, p16, p21, p27, RAB40C, COX 2, FOS, ERBB2, FGFR2, ABL1, ECOP, JAK2, MYC, MET, SIRT1, PDCD4, TRAF6, GMNN, and CCNE2) [213, 223-242], apoptosis (RECK, SMAD4, TRAIL, MCL1, BIM, XIAP, and PDK1) [243-250], and invasion and metastasis (pTEN, WNT 5a, EDNRA, ROR2, EPB41L3, MMP1, MMP10, HMGA2, ROBO1, TGF-[beta], EZH2, casein kinase 2, and ZEB) [251-262].
Status of Epstein-Barr Virus Coinfection with Helicobacter pylori in Gastric Cancer
Akatsuka et al., "Receptor activator of NF-[kappa]B ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6," Molecular and Cellular Biology, vol.
Optimal Zn-Modified Ca-Si-Based Ceramic Nanocoating with Zn Ion Release for Osteoblast Promotion and Osteoclast Inhibition in Bone Tissue Engineering
Extracellularly secreted IL-33 binds to ST2 and activates a heterodimeric receptor complex, comprising ST2 andinterleukin-1 receptor accessory protein (IL-1RAcP) on the plasma membrane, to recruit and activate myeloid differentiation factor 88 (MyD88), followed by activation of interleukin-1 receptor-associated kinase (IRAK) and tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) [5] (Figure 1).
IL-33 Acts to Express Schaffer Collateral/CA1 LTP and Regulate Learning and Memory by Targeting MyD88
Interestingly, miR-146 is a negative regulator of astrocytemediated inflammation [82], and upregulation of this miRNA decreases the expression of its target TRAF6 that is linked to seizure frequency in glioma patients suggesting that miR-146 could be involved in the epileptogenic focus surrounding the tumor [81].
MicroRNA in Glioblastoma: An Overview
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