TRKC


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AcronymDefinition
TRKCTransport Research Knowledge Centre (UK)
References in periodicals archive ?
TrkA for NGF, TrkB for BDNF and NT4, and TrkC for NT3) and p75 receptors.
Expression of neurotrophin 4 and its receptor tyrosine kinase B in reproductive tissues during the follicular and luteal phases in cows
In the study, NT-3 was found to be expressed at increased levels in aggressive human neuroblastomas and to block the ability of TrkC to induce tumour cell death by a process known as apoptosis.
Potential therapeutic targets for childhood cancer identified
Voluntary exercise increases neurotrophin-3 and its receptor TrkC in the spinal cord.
Activity-dependent plasticity in spinal cord injury
The presence of neurotrophins and the neurotrophin receptors p75 (p75NTR), tyrosine kinase A (TrkA), TrkB and TrkC are present in several immune cells.
Are there causal relationships between the development of the inflammatory diseases amyotrophic lateral sclerosis and asthma?
Relatives of trk are receptors for other neurotrophic factors--trkB seems to be a receptor for brain-derived neurotrophic factor, and trkC for neurotrophin-3.
Neurotrophic factors: a promising area of research is exploring the use of neuroprotective compounds called neurotrophic factors, which represent a new generation of therapeutic agents that can potentially prevent cell death and vision loss in patients with macular degeneration
Thus the trkA-expressing PC12 cells and chromaffin cells are in good contrast with central neurons expressing trkB or trkC corresponding to BDNF or NT-3 (see |9, 10~ for reviews).
Toward understanding of the molecular basis of loss of neuronal plasticity in ageing
Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25).
Molecular diagnostics of soft tissue tumors
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