Drugs such as anticholinergics (trihexyphenyl), benzodiazepines (eg, clonazepam and lorazepam), baclofen and tetrabenazine
are widely used, but side effects can be problematic (4).
These include anticholinergics (trihexyphenidyl, benztropine), GABAergic drugs (clonazepam, baclofen), antidopaminergics (tetrabenazine
) and mexiteline.
Lupin introduced a generic version of Valeant's Xenazine (tetrabenazine
) tablets, 12.5 mg and 25 mg, indicated for the treatment of chorea, or body spasms, associated with Huntington's disease.
History of tetrabenazine
use (100 mg/d) for 3 years.
Reddy's Laboratories Launches Tetrabenazine
Tablets in US
Although the paper reported a complete remission in neurological symptomology following tonsillectomy, cessation in neurological symptomology could not be purely linked to surgical intervention due to the initial initiation of twice-daily tetrabenazine
and the long-term use of prophylactic antibiotics.
She continued to decline despite subsequent trials of IV immunoglobulin (IVIg) (total dose of 2.5g/kg), prednisone, rituximab (1000mg once), and tetrabenazine
An important secret to the development of new therapies for Tourette is that we can alter these oscillations with rehabilitative therapies, cognitive behavioral intervention therapy (CBIT), medications such as (http://www.webmd.com/drugs/2/drug-151522/tetrabenazine-oral/details) tetrabenazine
or even deep brain stimulation, which involves a small straw-like probe being inserted into the brain.
, a dopamine depletor frequently used for hyperkinetic disorders, was not effective at 25 mg taken prior to coaching sessions.
Symptoms were unremitting, while the patient was started on tetrabenazine
with some subjective improvements in motor capabilities.
Both jaw opening and jaw closing OMD can be treated with oral antidystonic therapies such as tetrabenazine
, diazepam, and carbamazepine.