TQT

(redirected from Thorough QT)
AcronymDefinition
TQTThorough QT (Studies; heart muscle repolarization test)
TQTTotal Quality Transformation (quality initiative training system)
TQTTotal Quality Training
TQTTask Qualification Training
TQTTobacco Quota Trader (website; Tillsonburg, Ontario, Canada)
TQTTwenty Questions Test (cognitive behavior)
References in periodicals archive ?
In addition, Spero will conduct routine ancillary clinical pharmacology studies in parallel with the ADAPT-PO clinical trial, including a renal insufficiency study, a thorough QT prolongation study and a drug-drug interaction study.
There is a measurable impact on cardiac conduction seen in phase HI data and in the thorough QT study.
With this technology in place, INC may be able to eliminate the need for a separate, dedicated Thorough QT (TQT) study, which can cost between $2 million and $5 million.
is a global provider of integrated, technology-enhanced clinical trial management services: medical imaging solutions including electronic transfer, management, and independent review; cardiovascular safety monitoring including automated ECG, Thorough QT studies, Holter monitoring, ambulatory blood pressure monitoring and pulse wave analysis; and eClinical solutions for electronic data capture, randomization, clinical trial management, and clinical supply chain forecasting and optimization.
However, the new request for a thorough QT prolongation study, which assesses effects on cardiac repolarization, could push the resubmission back by more than a year.
"The first quarter saw an expected weakness in revenues resulting from the prior low levels of bookings from Thorough QT studies during the 2008-2009 recession," commented Dr.
These studies have been referred to as "thorough QT studies" because of the high density of EKG sampling and the rigid means of interpretation.
In addition to the planned pivotal Phase 3 trial, Spero will conduct routine ancillary clinical pharmacology studies in parallel with the Phase 3 trial, including a renal insufficiency study, a thorough QT prolongation study and a drug-drug interaction study.
The NDA submission also includes data from a pharmacokinetics (PK) trial evaluating the PK and safety of LEVADEX in smokers and non-smokers, a pharmacodynamics (PD) trial evaluating the acute effects of LEVADEX on pulmonary artery pressure, a thorough QT trial comparing the acute effects of a supra-therapeutic dose of LEVADEX on the cardiac QT interval as measured by electrocardiogram and a safety trial in adult asthmatics.
A third objective was to provide an estimate of the supra-therapeutic dose to be used in the thorough QT study planned as part of the new drug application.
Retigabine also caused a prolongation of the QT interval (electrical activity of the heart) when used at the highest dose in healthy volunteers in a thorough QT study.
In the CRL the FDA requested a thorough QT (tQT) study with exposures of exenatide higher than typical therapeutic levels of BYDUREON.