Toll-Like Receptor-4

Acronym	Definition
TLR4	Toll-Like Receptor-4

References in periodicals archive ?

The binding of LPS to CD14/LPS-binding protein and Toll-like receptor-4 triggers multiple signal cascades that activate nuclear factor-[kappa]B and p42/44 mitogen-activated protein kinase (MAPK) and lead to the expression of proinflammatory cytokines, including TNF-[alpha] (Triantafilou and Triantafilou 2002).

Lead increases lipopolysaccharide-induced liver injury through tumor necrosis factor-[alpha] overexpression by monocytes/macrophages: role of protein kinase C and p42/44 mitogen-activated protein kinase

The toll-like receptor-4 (TLR4; OMIM*603030), a member of a large family of transmembrane proteins, is predominantly expressed on monocytes and macrophages (1).

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology 2004;113:153-62.

LightTyper assay with locked-nucleic-acid-modified oligomers for genotyping of the toll-like receptor 4 polymorphisms A896G and C1196T

Bowman, "Endotoxin, toll-like receptor-4, and atherosclerotic heart disease," Current Cardiology Reviews, vol.

The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure

Conduah et al., "Innate immune signaling by toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors," Inflammatory Bowel Diseases, vol.

Immunomodulation by gut microbiota: role of toll-like receptor expressed by T cells

Kubes, "Platelets express functional Toll-like receptor-4 (TLR4)," Blood, vol.

Toll-Like Receptor 4 Signalling and Its Impact on Platelet Function, Thrombosis, and Haemostasis

Ding, "Toll-like receptor-4 and cytokine cascade in stroke after exercise, " Neurological Research, vol.

Selvaraj et al., "Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid [beta]-peptide and the membrane lipid peroxidation product 4-hydroxynonenal, " Experimental Neurology, vol.

TLR2 and TLR4 in the brain injury caused by cerebral ischemia and reperfusion

Kolb, "Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex," The Journal of Immunology, vol.

Danger signals in the initiation of the inflammatory response after myocardial infarction

Madrigal et al., "Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway," Biological Psychiatry, vol.

Possible involvement of TLRs and hemichannels in stress-induced CNS dysfunction via mastocytes, and glia activation

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