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TTKGTranstubular Potassium Gradient
TTKGTranstubuläre Kaliumgradient (German: Transtubular Potassium Gradient)
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TTKG indicates transtubular potassium gradient (a semiquantitative index of the activity of the potassium secretory process calculated as [urine K/(urine osmolality/plasma osmolality)]/plasma K); TSH: thyroidstimulating hormone; T4: serum thyroxine; T3: triiodothyronine.
The transtubular potassium gradient [([Osm.sub.plasma] x [K.sup.+.sub.urine])/([K.sup.+.sub.plasma] x [Osm.sub.urine])], although more commonly used to evaluate hyperkalemia, can be rapidly calculated and in this patient was found to be 13.3, which was inappropriately high (2) and confirmed excessive renal potassium loss.