The type III secretion system
of Pseudomonas aeruginosa: Infection by injection.
Also, Shigella is able to induce necrosis and apoptosis of host cells, the infected cells by Shigella spp or other dangerous pathogen bacteria rapidly lose membrane integrity due to the release of effector proteins such as cytoplasmic lactate dehydrogenase enzyme through the type III secretion system
and the exposure of phosphatidylserine.
Type III secretion system
effector proteins: double agents in bacterial disease and plant defense.
Haegman et al., "The Pseudomonas aeruginosa type III secretion system
plays a dual role in the regulation of caspase-1 mediated IL-1beta maturation," Journal of Cellular and Molecular Medicine, vol.
Previous studies have revealed that type III secretion system
plays a vital role in Pseudomonas burn infection.
After ingestion of contaminated food/water, STEC colonizes enterocytes of the large bowel with a characteristic attaching and effacing pathology via components of type III secretion system
(TTSS) encoded in the locus of enterocyte effacement (LEE) pathogenicity island.
These virulence affecting genes are potentially part of the flagellar type III secretion system
. The lack of this system in the flhD but not the fliA mutants would prevent the export of proteins that may contribute to virulence.
In 10 clinical and 1 environmental isolate there was presence of exoS, exoU, exoT and exoY, the genes involved in type III secretion system
thailandensis by real-time PCR targeting type III secretion system
Salmonella makes use of its own specialized "nano-syringe" called a type III secretion system
to take control of cells lining the intestinal track, which in turn causes the disease.
Translocation of bacterial 'toxic' secretions from invading Gram-negative pathogens into host/target cells was lauded as discovery of a novel process viz., vesicular exocytosis in prokaryotes (9,10) and was considered to add a new structural dimension of type III secretion system
Moreover, genes encoding type III secretion system
(T3SS2) located on this chromosome was previously considered as being related to the pathogenicity of V.