On the basis of these findings, a pathological diagnosis of UESL was made.
The pathological findings are consistent with metastases of the UESL. A chemotherapy regimen with olaratumab plus doxorubicin was received.
Undifferentiated embryonal sarcoma of the liver (UESL) is a relatively new distinct clinicopathologic entity that describes a rare malignancy arising from the primitive mesenchymal tissue of the liver .
Supporting this theory, similar genetic abnormalities were described in both MH and UESL and especially chromosome 19 aberrations [11-13].
UESL may occur in any part of the liver but is most commonly found in the right lobe as a single, rapidly growing mass.
Precise localization of the tumor and its relationship with the major vessels are crucial in defining its resectability, which represents the most important prognostic factor in patients with UESL.
No specific laboratory finding is associated with UESL. Liver test results and neoplastic markers are usually normal in these patients.
Radiological findings of UESL are also nonspecific.
The solid component of UESL appears sarcomatoid (Figure 1) with a myxoid background.
Five patients--4 females and 1 male, ranging in age from 5 years to 11 years--were diagnosed with UESL. Follow-up ranged in duration from 58 months to 15 years.
Willis first described the pathology of UESL in 1962, classifying it as a rhabdomyoblastic mixed tumour.
At first, imaging studies of UESL may appear discordant: the mass appears solid on ultrasound, but predominantly cystic on CT Scan and magnetic resonance imaging (MRI).