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But we did not find any significant difference between UKALL and BFM protocols (p>0.05).
Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomized controlled trial.
It is a continuation of UKALL 2003, which led to the introduction of a new method of monitoring the response to chemotherapy and led to a marked improvement in cure rates.
Sarah Lawson, Birmingham Children's Hospital Consultant Paediatric Haematologist, and National Coordinator for the UKALL 2011 trial, said: "We are incredibly grateful to Cure Leukaemia for supporting our team at Birmingham Children's Hospital to deliver these vital leukaemia trials.
This dose was chosen with reference to the MRC UKALL XI protocol for whole brain radiotherapy in ALL.
Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172).
(5) Nonstandard abbreviations, ALL, acute lymphoblastic leukemia; NHL, non-Hodgkin lymphoma; CNS, central nervous system; (HD)MTX, (highdose) methotrexate; BFM, Berlin-Frankfurt-Munster Cooperative Group; UKALL, United Kingdom ALL Cooperative Group; COG, Children's Oncology Group; AUC, area under curve; and CCR, continuous complete remission.
T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993).
Comparison of bone marrow transplant and chemotherapy for relapsed childhood acute lymphoblastic leukaemia: The MRC UKALL X experience.
Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993.
Cytogenetics and prognosis in childhood lymphoblastic leukaemia: results of MRC UKALL X.
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