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USP7Ubiquitin Specific Protease 7 (gene)
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Recently, a study has revealed that USP7 is related to osteogenic differentiation of human adipose-derived stem cells (hASCs) [71].
Sixma, "Regulation of USP7: a high incidence of E3 complexes," Journal of Molecular Biology, vol.
In addition, USP7 stabilizes MDM2, causing p53 levels go down, thus allowing cancer cells to proliferate.
Yoshitane et al., "USP7 and TDP-43: pleiotropic regulation of cryptochrome protein stability paces the oscillation of the mammalian circadian clock," PLoS ONE, vol.
Wood et al., "The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X" Traffic, vol.
Moreover, expression levels of cold-regulated genes like KIN17, LEA2/4, USP7, MAT1 and COR413 were highlighted up 27-143 times than those before cold processing (Fig.
The DUBs, A20, CYLD, USP2, USP4, USP7, USP10, USP18, USP21, and USP25 terminate NF-[kappa]B signaling by removing K63-linked ubiquitin chains from signaling molecules [101-123].