UTROSCTUterine Tumor Resembling Ovarian Sex Cord Tumor (oncology)
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It should also be emphasized that neoplastic endometrial stroma should not be found in the histological analysis of UTROSCT [9].
In a systematic review published in 2018 that evaluated prognostic factors of recurrence in UTROSCT, recurrence rates of 6.3% were found for the 79 patients evaluated.
Although there is currently no consensus with respect to the follow-up regimen for cases of UTROSCT, the patient in the present report is undergoing annual outpatient follow-up, with no signs of metastasis or tumor recurrence twelve months after surgery.
This is the first reported case of a UTROSCT in a prolapsed fibroid protruding into the vagina through the cervix.
Khan, "Uterine tumor resembling ovarian sex cord tumor (UTROSCT), case report with literature review," International Archives of Medicine, vol.
Caption: Figure 1: UTROSCT removed from the patient's uterus.
(11,22) Furthermore, as described above, endometrial stromal tumors, including low-grade endometrial stromal sarcoma, endometrial stromal nodule, and ESTSCLE, show t(7; 17)(p15; q21) translocation; however, no specific or significant genetic alteration, including t(7; 17), is observed in UTROSCT. (17,18)
The neoplastic cells are invariably positive for smooth muscle actin, caldesmon, and CD99 in a more diffuse fashion, which may be observed in UTROSCT but to a lesser extent.
However, calretinin, inhibin, cytokeratin 7, and epithelial membrane antigen are negative, in contrast to UTROSCT. This tumor also has a benign behavior.
A UTROSCT is generally discovered only after hysterectomy, and most of the patients reported so far were managed with hysterectomy with or without bilateral salpingo-oophorectomy.
Uterine tumors resembling ovarian sex cord tumors (UTROSCT) lack the JAZF1-JJAZ1 translocation frequently seen in endometrial stromal tumors.
Macroscopic image of uterine tumor resembling ovarian sex cord tumor (UTROSCT): Tan-yellow to tan -white, cut surfaces of an UTROSCT (upper left, lower left, and lower right), in contrast to the whorled tan-white cut surface of an intramural leiomyoma (upper right) present in the same hysterectomy specimen.