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VA-HITVeterans Affairs Cooperative HDL (High Density Lipoprotein) Cholesterol Intervention Trial
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In the VA-HIT trial (55), NMR-measured concentrations of total and small HDL particles were independent predictors of recurrent cardiovascular disease.
Rubins HB, Robins SJ, Collins D, et al, for the VA-HIT Study Group: Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol.
Another study, known as VA-HIT (VA High Density Lipoprotein Intervention Trial, conducted by the Department of Veteran Affairs), showed that raising HDL-C levels in patients with low HDL-C with a fibrate significantly reduced coronary heart disease events.