Yang S et al  found VEGF-A
expression in 51.5% of RCC cases, which was significantly higher than the rate of expression in normal renal tissue surrounding the carcinoma.
La interaccion de VEGF-A
con sus receptores es esencial para establecer un sistema vascular funcional durante la embriogenesis y al comienzo del desarrollo postnatal e incluso en procesos patologicos como cancer.
- US-based clinical stage biotechnology company Moderna, Inc., (NASDAQ: MRNA) has published a Phase 1a/b study in Nature Communications showing the potential of mRNA encoding for vascular endothelial growth factor A (VEGF-A
) as a regenerative therapeutic, the company said.
No difference in VEGF-A
expression was found in the control and vehicle groups.
Ranibizumab (Lucentis, Novartis, Switzerland), a fragment of a human monoclonal antibody against VEGF-A
selectively binds all isoforms of VEGF-A
(VEGF110, VEGF121, and VEGF165), was applied at a concentration of 0.125 mg/mL.
levels and VEGF gene expression in cerebrospinal fluid of 32 neuro-Behcet's disease patients and compared them with the control group.
Haigh et al., "Glomerular-specific alterations of VEGF-A
expression lead to distinct congenital and acquired renal diseases," Journal of Clinical Investigation, vol.
Comparative study between VEGF-A
and CA-125 in diagnosis and follow-up of advanced endometriosis after conservative laparoscopic surgery.
Results: It was found that VEGF-A
levels were significantly raised in women with RIF compared to healthy controls (362.9 vs.
Serum vascular endothelial growth factor-A (VEGF-A
) as a biomarker in squamous cell carcinoma of head and neck patients undergoing chemoradiotherapy.
binds to and activates the tyrosine kinase receptors, VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1) .
has been considerably studied on the account of its ability to promote angiogenic effects via one of its receptors, VEGFR2 .