's sixth president, was recently named President of the Year by the North Carolina State Board of Community Colleges for her leadership and commitment to the community college mission within the state's community college system.
In neuronal cells, [Ca.sup.2+] influx mediated by NMDAR and VGCC
elicits RyR-mediated CICR, which operates as an amplification mechanism of postsynaptic [Ca.sup.2+] entry signals .
Lambert-Eaton myasthenic syndrome (LEMS) is a rare neuromuscular junction disorder resulting from the development of auto-antibodies against voltage-gated calcium channels (VGCCs
) in pre-synaptic terminals (1).
Looking back on his experience, Paul said that his favorite classes at VGCC
were his math, science and Spanish classes.
This finding could be explained by TNF-induced overexpression of TRPV1 or by enhanced inhibition of VGCC
NSCLC: Non-small cell lung cancer VGCC
: Voltage-gated calcium channel qRT-PCR: Quantitative reverse transcription polymerase chain reaction TMA-IHC: Tissue microarray immunohistochemistry analysis TNM: Tumor node metastasis ER: Endoplasmic reticulum FFPE: Formalin-fixed paraffin-embedded OS: Overall survival HR: Hazard ratio.
facilitation underlying synaptic facilitation (Fig.
NMDA receptor; STDP, spike timing-dependent plasticity; VGCC
, voltage-gated calcium channel.
Nimodipine, a VGCC
antagonist was observed to reduce opioid requirement in cancer patients for management of pain, in a double-blind placebo controlled study, though contradictory finding has also been reported.
A large body of experimental data showed that calcium [12, 13], potassium, and other ion channels were involved in the mechanism of action of the central and peripheral nervous system  Voltage-gated calcium channels (VGCC
) may be involved in the regulation of super excited states associated with a state of chronic pain of the primary afferent neurons .
Verderio et al., "Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC
[alpha]2[delta]-1 subunit," Neuron, vol.
Our previous study also suggested that magnolol's ability to inhibit colonic contraction induced by high [K.sup.+], carbachol, and 5-HT in guinea pig involves blocking the influx of [Ca.sup.2+] through voltage-gated calcium channels (VGCC
) and inhibiting [Ca.sup.2+] release from the sarcolemmal membrane (Bian et al.