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The facility and VGTI are currently both under receivership.
The VGTI team found that mostly central memory T-cells make up the latent HIV reservoir in people who start ART early and respond well with large CD4 cell gains, while people with poor CD4 cell recovery have more latently infected transitional memory cells.
The research team, led by Louis Picker, M.D., associate director of the OHSU VGTI and director of the VGTI's vaccine program, produced a vaccine candidate that programs the immune system of non-human primates to respond more swiftly to the presence of a primate version of HIV than it normally would.
The VGTI researchers tested their vaccine candidate in rhesus macaque monkeys at the Oregon National Primate Research Center using a monkey form of HIV called Simian Immunodeficiency Virus (SIV).
Rafick-Pierre Sekaly, current scientific director for VGTI Florida, a former scientist at the University of Montreal, as saying.
"HIV appears to be vulnerable when it is first introduced into mucosal surfaces in the body," said Louis Picker, M.D., associate director of the OHSU VGTI and director of the VGTI's vaccine program.
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