The company's most advanced programme is an improved next-generation coagulation Factor VIIa
variant, marzeptacog alfa (activated), that has successfully completed an intravenous Phase 1 clinical trial in individuals with severe hemophilia A or B.
Thromboembolic adverse events after use of recombinant human coagulation factor VIIa
LFB has been producing limited amounts of Factor VIIa
in the milk of rabbits in France.
11,12) Treatment strategies to control active bleeding include the use of desmopressin (DDAVP), Factor VIII concentrate, activated prothrombin complex or APC (FEIBA - Anti-inhibitor coagulant factor), and Recombinant VIIa
is a naturally occurring protein that plays an important role in the coagulation cascade.
GTC, together with its collaboration partner LFB Biotechnologies, has established the transgenic rabbit production system for its recombinant form of human coagulation factor VIIa
(rhFVIIa) which is being developed for the treatment of patients with hemophilia.
In these instances a Factor VIIa
is used to bypass inhibitors and help these individuals to form clots.
Key Words: recombinant factor VIIa
, Crohn disease, surgery, bleeding, hemorrhage
Treatment of traumatic bleeding with recombinant factor VIIa
Lewis finds a new home viia
the nurses' noticeboard at St Hugh's Hospital.
He also keeps recombinant factor VIIa
nearby when performing these surgeries or any surgery that risks massive hemorrhage.
Relationships between homocysteine, factor VIIa
, and thrombin generation in acute coronary syndromes.