VIN 3Vulvar Intraepithelial Neoplasia Grade 3
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When an excision for high-grade dysplasia is done (formerly VIN 3), detection of occult carcinoma was found in up to 3.2% in one large review (Gynecol Oncol.
So the ISVVD revised the classification system to include only high-grade VIN--the old VIN 2 and VIN 3. HPV-associated lesions with dysplastic cells confined to the lower third of the epithelium are managed like genital warts, with observation for spontaneous regression or treatment with topical therapy or surgery.