VLDL-CVery Low Density Lipoprotein-Cholesterol
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The mean +- SD values of total serum cholesterol, triglycerides, VLDL-C, LDL-C, and HDL-C were found to be 174.0 +- 54.1, 241.2 +- 142.4, 44.3 +- 22.8, 95.2 +- 49.0 and 35.0 +- 10.8 mg/dl respectively.
Non-significant differences in HDL values were observed in rats treated with AGE, while all other treatments have shown the highly significant (EGE; 32%, Insulin; 50%, and NSO; 63%, p0.05) increase in low density lipoproteins (LDL-C) and slightly significant increase (36%, p<0.05) in very low density lipoproteins (VLDL-C) contents was noted in diabetic rats compared to the normal rats.
Serum TC, LDL-C, VLDL-C and TG were negatively correlated with STD.
It was observed that serum total cholesterol, triglycerides (TG), HDL-C, and VLDL-C showed significantly higher changes (p<0.001) in the overall patients when compared with control subjects.
In present study, the change in LDL-C cholesterol was not significant in patients and controls, however serum VLDL-C levels rose significantly (P<0.001) in the eclampsia group, which may be due to hyper-triglyceridemia leading to enhanced entry of VLDL that carries endogenous triglycerides into circulation.
In this study, in the fasting state, 37% of cases had total VLDL-C levels of >40 mg/dL as compared with that of the control group whereas only 8% of the controls had VLDL-C levels of >40 mg/dL.
Serum lipid Profile: For lipid profile, GBE treated group showed significant (Pless than 0.0001) enhancement in HDL-C concentration and with no effect on TC, VLDL-C and LDL-C levels.
HDL-C, LDL-[C.sub.[beta]Q], and VLDL-C concentrations were determined as described previously (10).
Pearson's correlation showed a significant positive association between CAT and TC, TG, and VLDL-C, and between MDA, HDL-C and LDL-C [Table 4].
Patients with OH had statistically significant higher levels of TC (260.04 [+ or -] 11.07mg/dl, p<0.001), TG (171.76 [+ or -] 1.8mg/dl, p<0.05), LDL-C (151.635 [+ or -] 8.44mg/dl, p<0.001) and VLDL-C (34.35 [+ or -] 4.06mg/dl, p<0.05) when compared with controls.
Las determinaciones del colesterol ligado a lipoproteinas de muy baja densidad (VLDL-C) y de baja densidad (LDL-C), se estimaron mediante la formula de Friedewald: VLDL-C = TG/5 y para LDL-C = CT-(HDL-C + VLDL-C) (FRIEDEWALD et al., 1972).