VLDLCVery Low Density Lipoprotein Cholesterol
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As previously reported by us, yacon roots exhibit a lipid lowering effect, mainly reducing serum triglycerides and VLDLc levels, in normal and diabetic rats [17, 25].
TC, TAG, VLDLc, and LDLc of HFD-fed rats increased significantly with concomitant decreased HDLc in comparison with control rats.
Data in table 4 show significant increase in the mean value of serum concentration of TG, LDLc and VLDLc in obese animals (control +ve) Consumption of 10% and 20% cooked or 10% germinated faba bean reduced these parameters at Pless than 0.001, while 20% germinated faba bean reduced these values at Pless than 0.05and0.01, as compared to the control animals.
In addition, both harmful fractions LDLc and VLDLc were significantly increased (P=0.05) from 10.2 mg/dl and 12.8 mg/dl
The Pearson correlation was used to test whether TSH, fT4 and fT3 was correlated with TC, LDL-C, HDL-C, TG, VLDLC, TC/HDL-C and LDL/HDL-C.
Dyslipidaemia associated with HAART is most commonly seen in hypertriglyceridaemia (probably due to an overproduction of very-low-density lipoprotein cholesterol (VLDLC)), followed by an increase in total cholesterol and a decrease in serum HDLC.
Un resultado similar se evidencio con el resto de las variables bioquimicas, con excepcion de los trigliceridos (178,5 [+ o -] 77,2 mg/dL; 139,6 [+ o -] 57,3 mg/dL; 155,6 [+ o -] 74,7 mg/dL, respectivamente) y las VLDL-C (33,9 [+ o -] 16,4 mg/dL; 27,3 [+ o -] 11,5 mg/dL; 29,1 [+ o -] 14,8 mg/dL, respectivamente) que estuvieron significativamente elevados en los sujetos fumadores (trigliceridos: p < 0,01 y VLDLC: p < 0,05).
Plasma LDL-cholesterol (LDL-C), VLDL-cholesterol (VLDLC) and atherogenic index (AI) were calculated (Friedewald et al., 1972).
Densitometric scanning of electrophoretograms (HYRYS densitometer 1012; SEBIA) at 540 nm, using a green filter (or at 420 nm, using a blue filter), allowed quantification of colorimetric intensities of bands corresponding to LDLC, of an intermediate band corresponding to VLDL-cholesterol (VLDLC) and lipoprotein(a) [Lp(a)], and of a band corresponding to HDLC (Fig.